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Integrative bioinformatics analysis for identifying the mitochondrial-related gene signature associated with immune infiltration in premature ovarian insufficiency

8 Oct 2024

Abstract excerpt

BACKGROUND: Premature ovarian insufficiency (POI) is a reproductive disorder characterized by the cessation of ovarian function before the age of 40. Although mitochondrial dysfunction and immune disorders are believed to contribute to ovarian damage in POI, the interplay between these factors remains understudied. METHODS: In this research, transcriptomic data related to POI were obtained from the NCBI GEO...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39379953
DOI: 10.1186/s12916-024-03675-7

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