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Gut stem cells in tissue renewal and disease: methods, markers, and myths

29 May 2012

Abstract excerpt

Homeostasis in adult tissue is maintained by the activity of a minor population of long-lived resident stem cells. These adult stem cells are defined by two essential attributes, self-renewal and multipotency, and their physiological activity is regulated by a specialized microenvironment, the stem cell niche. These adult stem cells are generally considered to divide infrequently, and cell expansion is mainly...

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PMID: 22644962
DOI: 10.1002/wsbm.1176

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