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Article

Colorectal polyps increase the glycolytic activity

5 Jun 2023

Abstract excerpt

In colorectal cancer (CRC) energy metabolism research, the precancerous stage of polyp has remained rather unexplored. By now, it has been shown that CRC has not fully obtained the glycolytic phenotype proposed by O. Warburg and rather depends on mitochondrial respiration. However, the pattern of metabolic adaptations during tumorigenesis is still unknown. Understanding the interplay between genetic and metabolic...

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PMID: 37342183
DOI: 10.3389/fonc.2023.1171887

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