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Metabolic Reprogramming Helps to Define Different Metastatic Tropisms in Colorectal Cancer

25 Jul 2022

Abstract excerpt

Approximately 25% of colorectal cancer (CRC) patients experience systemic metastases, with the most frequent target organs being the liver and lung. Metabolic reprogramming has been recognized as one of the hallmarks of cancer. Here, metabolic and functional differences between two CRC cells with different metastatic organotropisms (metastatic KM12SM CRC cells to the liver and KM12L4a to the lung when injected in...

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PMID: 35957902
DOI: 10.3389/fonc.2022.903033

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