Article
Clinical Validation of the Unparalleled Sensitivity of the Novel Allele-Discriminating Priming System Technology-Based EGFR Mutation Assay in Patients with Operable Non-Small Cell Lung Cancer.
Cancer research and treatment - 1 Jan 2024
Park Il-Hyun, Son Dae-Soon, Choi Yoon-La, Choi Ji-Hyeon, Park Ji-Eun, Jeon Yeong Jeong, Cho Minseob, Kim Hong Kwan, Choi Yong Soo, Shim Young Mog, Kang Jung Hee, Park Suzy, Lee Jinseon, Kim Sung-Hyun, Lee Byung-Chul, Kim Jhingook
Abstract excerpt
PURPOSE: Recently, we developed allele-discriminating priming system (ADPS) technology. This method increases the sensitivity of conventional quantitative polymerase chain reaction up to 100 folds, with limit of detection, 0.01%, with reinforced specificity. This prospective study aimed to develop and validate the accuracy of ADPS epidermal growth factor receptor (EGFR) Mutation Test Kit using clinical specimens....
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