Article
Genome wide association study identifies a novel putative mammographic density locus at 1q12-q21.
International journal of cancer - 15 May 2015
Fernandez-Navarro Pablo, González-Neira Anna, Pita Guillermo, Díaz-Uriarte Ramón, Tais Moreno Leticia, Ederra María, Pedraz-Pingarrón Carmen, Sánchez-Contador Carmen, Vázquez-Carrete Jose Antonio, Moreo Pilar, Vidal Carmen, Salas-Trejo Dolores, Stone Jennifer, Southey Melissa C, Hopper John L, Pérez-Gómez Beatriz, Benitez Javier, Pollan Marina
Abstract excerpt
Mammographic density (MD) is an intermediate phenotype for breast cancer. Previous studies have identified genetic variants associated with MD; however, much of the genetic contribution to MD is unexplained. We conducted a two-stage genome-wide association analysis among the participants in the "Determinants of Density in Mammographies in Spain" study, together with a replication analysis in women from the...
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