Article
Investigating the structural impact of Omicron RBD mutation on antibody escape and receptor management.
Journal of biomolecular structure & dynamics - 1 Jun 2024
Saini Samvedna, Pareekh Savita, Kumar Yatender
Abstract excerpt
The SARS-CoV-2 Variant B.1.1.5291 evolved rapidly in late November 2021 from the existing mutants sparking fear worldwide owing to its infamous immune escape from a varied class of neutralising antibodies. To assess the structural behaviour of Omicron-Receptor Binding Domain (RBD) upon interacting with cross-reactive CR3022 antibody, we investigated the computational approach of structural engagement in B.1.1529...
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