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Article

HMGB3 promotes the malignant phenotypes and stemness of epithelial ovarian cancer through the MAPK/ERK signaling pathway.

Cell communication and signaling : CCS - 16 Jun 2023

Ma Hanlin, Qi Gonghua, Han Fang, Gai Panpan, Peng Jiali, Kong Beihua

Abstract excerpt

BACKGROUND: Ovarian cancer, particularly epithelial ovarian cancer (EOC), is the leading cause of cancer-related mortality among women. Our previous study revealed that high HMGB3 levels are associated with poor prognosis and lymph node metastasis in patients with high-grade serous ovarian carcinoma; however, the role of HMGB3 in EOC proliferation and metastasis remains unknown. METHODS: MTT, clonogenic, and EdU...

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Topics

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Share to Carcinoma, Ovarian Epithelial
Share to Cell Line, Tumor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Movement

Share to Cell Proliferation

Share to Gene Expression Regulation, Neoplastic

Share to Ovarian Neoplasms

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Source

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Identifiers

PMID: 37328851
DOI: 10.1186/s12964-023-01172-7
PMCID: PMC10273509

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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