Article
Harmonized molecular classification; assessment of a single-test ProMisE NGS tool.
Gynecologic oncology - 1 Aug 2023
Jamieson Amy, McConechy Melissa K, Lum Amy, Leung Samuel, Thompson Emily F, Senz Janine, Talhouk Aline, Huntsman David G, Bashashati Ali, Gilks C Blake, McAlpine Jessica N
Abstract excerpt
OBJECTIVES: Despite recommendations for integrating molecular classification of endometrial cancers (EC) into pathology reporting and clinical management, uptake is inconsistent. To assign ProMisE subtype, all molecular components must be available (POLE mutation status, mismatch repair (MMR) and p53 immunohistochemistry (IHC)) and often these are assessed at different stages of care and/or at different centres...
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