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Article

Targeted Molecular Testing in Endometrial Carcinoma: Validation of a Clinically Driven Selective ProMisE Testing Protocol.

International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists - 1 Jul 2023

Talhouk Aline, Jamieson Amy, Crosbie Emma J, Taylor Alexandra, Chiu Derek, Leung Samuel, Grube Marcel, Kommoss Stefan, Gilks C Blake, McAlpine Jessica N, Singh Naveena

Abstract excerpt

Incorporation of molecular classification into clinicopathologic assessment of endometrial carcinoma (EC) improves risk stratification. Four EC molecular subtypes, as identified by The Cancer Genome Atlas, can be diagnosed through a validated algorithm Pro active M olecular R is k Classifier for E ndometrial Cancer (ProMisE) using p53 and mismatch repair (MMR) protein immunohistochemistry (IHC), and DNA...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36731023
DOI: 10.1097/PGP.0000000000000898

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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