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Metagenomics of the Gut Microbiome in Parkinson's Disease: Prodromal Changes

14 Jun 2023

Abstract excerpt

OBJECTIVE: Prior studies on the gut microbiome in Parkinson's disease (PD) have yielded conflicting results, and few studies have focused on prodromal (premotor) PD or used shotgun metagenomic profiling to assess microbial functional potential. We conducted a nested case-control study within 2 large epidemiological cohorts to examine the role of the gut microbiome in PD. METHODS: We profiled the fecal metagenomes...

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PMID: 37314861
DOI: 10.1002/ana.26719

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