Article
Recognition of Nucleophosmin Mutant Gene Expression of Leukemia Cells Using Raman Spectroscopy.
Applied spectroscopy - 1 Jul 2023
Li Mingxin, Wu Yihui, Chi Mingbo, Wang Yimeng, Zhu Mingyao, Gao Sujun
Abstract excerpt
As a label-free, nondestructive, and in situ detection method, Raman spectroscopy analysis of single cells has potential application value in biomedical fields such as cancer diagnosis. In this study, the Raman spectral characteristics of nucleophosmin (NPM1)-mutant acute myeloid leukemia (AML) cells and nonmutated AML cells were investigated, and the reasons for the differences in spectral peaks were explained...
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