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Raman Spectroscopy of Blood Serum for Essential Thrombocythemia Diagnosis: Correlation with Genetic Mutations and Optimization of Laser Wavelengths.

Cell biochemistry and biophysics - 1 Sept 2024

Aday Aynur, Bayrak Ayşe Gül, Toraman Suat, Hindilerden İpek Yönal, Nalçacı Meliha, Depciuch Joanna, Cebulski Jozef, Guleken Zozan

Abstract excerpt

Essential thrombocythemia (ET) is a type of myeloproliferative neoplasm that increases the risk of thrombosis. To diagnose this disease, the analysis of mutations in the Janus Kinase 2 (JAK2), thrombopoietin receptor (MPL), or calreticulin (CALR) gene is recommended. Disease poses diagnostic challenges due to overlapping mutations with other neoplasms and the presence of triple-negative cases. This study explores...

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PMID: 38847941
DOI: 10.1007/s12013-024-01333-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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