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Article

TCA Cycle Rewiring as Emerging Metabolic Signature of Hepatocellular Carcinoma

25 Dec 2019

Abstract excerpt

Hepatocellular carcinoma (HCC) is a common malignancy. Despite progress in treatment, HCC is still one of the most lethal cancers. Therefore, deepening molecular mechanisms underlying HCC pathogenesis and development is required to uncover new therapeutic strategies. Metabolic reprogramming is emerging as a critical player in promoting tumor survival and proliferation to sustain increased metabolic needs of...

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PMID: 31881713
DOI: 10.3390/cancers12010068

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