Article
Prevalence of Janus Kinase 2 mutations in patients with unusual site venous thrombosis.
Medicina - 1 Jan 2011
Basquiera Ana Lisa, Tabares Aldo H, Soria Néstor, Salguero Miriam, Ryser Ricardo, García Juan José
Abstract excerpt
We aimed to study patients with splanchnic vein thrombosis (SVT) and cerebral vein thrombosis (CVT) searching for JAK2 mutations. We evaluated 14 patients (median age: 41.5 years) with portal vein thrombosis (PVT) = 7; mesenteric vein thrombosis (MVT) = 3; and CVT = 4. JAK2 V617F was assessed by allele specific PCR of peripheral blood DNA. In addition, DNA was sequenced for other JAK2 mutations. Other inherited...
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