Article
Asian Thoracic Oncology Research Group (ATORG) Expert Consensus Statement on MET Alterations in NSCLC: Diagnostic and Therapeutic Considerations.
Clinical lung cancer - 1 Dec 2022
Ahn Myung-Ju, Mendoza Marvin Jonne L, Pavlakis Nick, Kato Terufumi, Soo Ross A, Kim Dong-Wan, Liam Chong Kin, Hsia Te-Chun, Lee Chee Khoon, Reungwetwattana Thanyanan, Geater Sarayut, Chan Oscar Siu Hong, Prasongsook Naiyarat, Solomon Benjamin J, Nguyen Thi Thai Hoa, Kozuki Toshiyuki, Yang James Chih-Hsin, Wu Yi-Long, Mok Tony Shu Kam, Tan Daniel Shao-Weng, Yatabe Yasushi
Abstract excerpt
Non-small cell lung cancer (NSCLC) is a heterogeneous disease, with many oncogenic driver mutations, including de novo mutations in the Mesenchymal Epithelial Transition (MET) gene (specifically in Exon 14 [ex14]), that lead to tumourigenesis. Acquired alterations in the MET gene, specifically MET amplification is also associated with the development of epidermal growth factor receptor (EGFR) tyrosine kinase...
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