Article
3DVizSNP: a tool for rapidly visualizing missense mutations identified in high throughput experiments in iCn3D.
BMC bioinformatics - 9 Jun 2023
Sierk Michael, Ratnayake Shashikala, Wagle Manoj M, Chen Ben, Park Brian, Wang Jiyao, Youkharibache Philippe, Meerzaman Daoud
Abstract excerpt
BACKGROUND: High throughput experiments in cancer and other areas of genomic research identify large numbers of sequence variants that need to be evaluated for phenotypic impact. While many tools exist to score the likely impact of single nucleotide polymorphisms (SNPs) based on sequence alone, the three-dimensional structural environment is essential for understanding the biological impact of a nonsynonymous...
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