Article
DisCanVis: Visualizing integrated structural and functional annotations to better understand the effect of cancer mutations located within disordered proteins.
Protein science : a publication of the Protein Society - 1 Jan 2023
Deutsch Norbert, Pajkos Mátyás, Erdős Gábor, Dosztányi Zsuzsanna
Abstract excerpt
Intrinsically disordered proteins (IDPs) play important roles in a wide range of biological processes and have been associated with various diseases, including cancer. In the last few years, cancer genome projects have systematically collected genetic variations underlying multiple cancer types. In parallel, the number and different types of disordered proteins characterized by experimental methods have also...
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