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Article

Graph-ETMB: A graph neural network-based model for tumour mutation burden estimation.

Computational biology and chemistry - 1 Aug 2023

Yang Wanting, Qiang Yan, Wu Wei, Xin Jialong

Abstract excerpt

As a critical indicator of how easily the human immune system recognizes tumour cells, tumour mutational burden (TMB) is widely used to identify the potential effectiveness of immune checkpoint inhibitor therapy. However, the difficulties associated with the whole exome sequencing (WES) process, such as high tissue sampling requirements, high costs, and long turnaround times, have hindered the widespread clinical...

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PMID: 37285654
DOI: 10.1016/j.compbiolchem.2023.107900

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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