Article

Predicting tumour mutational burden from histopathological images using multiscale deep learning

2020-06-16

Abstract excerpt

<h4>ABSTRACT</h4> Tumour mutational burden (TMB) is an important biomarker for predicting response to immunotherapy in cancer patients. Gold-standard measurement of TMB is performed using whole exome sequencing (WES), which is not available at most hospitals owing to its high cost, operational complexity, and long turnover times. We developed a machine learning algorithm, Image2TMB, which can predict TMB from rea...

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Literature Corpus work: ae1769a7-e852-5c85-9eba-65c8cbef8f99
DOI: 10.1101/2020.06.15.153379

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