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Targeted IS-element sequencing uncovers transposition dynamics during selective pressure in enterococci

2 Jun 2023

Abstract excerpt

Insertion sequences (IS) are simple transposons implicated in the genome evolution of diverse pathogenic bacterial species. Enterococci have emerged as important human intestinal pathogens with newly adapted virulence potential and antibiotic resistance. These genetic features arose in tandem with large-scale genome evolution mediated by mobile elements. Pathoadaptation in enterococci is thought to be mediated in...

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PMID: 37267422
DOI: 10.1371/journal.ppat.1011424

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