Article
Factors associated with the emergence of integrase resistance mutations in patients failing dual or triple integrase inhibitor-based regimens in a French national survey.
The Journal of antimicrobial chemotherapy - 12 Aug 2021
Marcelin Anne-Genevieve, Charpentier Charlotte, Bellecave Pantxika, Abdi Basma, Chaix Marie-Laure, Ferre Virginie, Raymond Stephanie, Fofana Djeneba, Bocket Laurence, Mirand Audrey, Le Guillou-Guillemette Helene, Montes Brigitte, Amiel Corinne, Pallier Coralie, Fafi-Kremer Samira, De Monte Anne, Alessandri-Gradt Elodie, Scholtes Caroline, Maillard Anne, Jeulin Helene, Bouvier-Alias Magali, Roussel Catherine, Dos Santos Georges, Signori-Schmuck Anne, Dina Julia, Vallet Sophie, Stefic Karl, Soulié Cathia, Calvez Vincent, Descamps Diane, Flandre Philippe
Abstract excerpt
BACKGROUND: Successful 2-drug regimens (2DRs) for HIV were made possible by the availability of drugs combining potency and tolerability with a high genetic barrier to resistance. How these deal with resistance development/re-emergence, compared with 3DRs, is thus of paramount importance. MATERIALS AND METHODS: A national survey including patients who were either naive or experienced with any 2DR or 3DR but...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.