Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gene Panel Sequencing Analysis Revealed a Strong Contribution of Rare Coding Variants to the Risk of Parkinson's Disease in Sporadic Moroccan Patients.

Journal of molecular neuroscience : MN - 1 Jun 2023

Smaili Imane, Tibar Houyam, Rahmani Mounia, Machkour Najlaa, Razine Rachid, Darai Hajar Naciri, Bouslam Naima, Benomar Ali, Regragui Wafa, Bouhouche Ahmed

Abstract excerpt

Parkinson's disease (PD) is a neurodegenerative movement disorder which can be either familial or sporadic. While it is well known that monogenic mutations are not a very common cause of PD, GWAS studies have shown that an additional fraction of the PD heritability could be explained by rare or common variants. To identify the rare variants that could influence the risk of PD in the Moroccan population, a cohort...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genes, Recessive
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome-Wide Association Study

Share to Leucine-Rich Repeat Serine-Threonine Protein Kinase-2

Share to Mutation

Share to Parkinson Disease

Source

Identifiers

PMID: 37256495
DOI: 10.1007/s12031-023-02128-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gene Panel Sequencing Analysis Revealed a Strong Contribution of Rare Coding Variants to the Risk of Parkinson's Disease in Sporadic Moroccan Patients.PMID 37256495Read ↗

Gene Panel Sequencing Identifies Novel Pathogenic Mutations in Moroccan Patients with Familial Parkinson Disease.Semantic proximity Read ↗

The Genetic Architecture of Parkinson's Disease in Morocco: Highlighting a Predominance of Mendelian Genes.Semantic proximity Read ↗

Mutation Analysis of Consanguineous Moroccan Patients with Parkinson’s Disease Combining Microarray and Gene PanelSemantic proximity Read ↗

LRRK2 G2019S Mutation: Prevalence and Clinical Features in Moroccans with Parkinson’s DiseaseSemantic proximity Read ↗

A Novel Homozygous p.L539F Mutation Identified in PINK1 Gene in a Moroccan Patient with Parkinsonism.Semantic proximity Read ↗

Novel and reported variants in Parkinson's disease genes confer high disease burden among Indians.Semantic proximity Read ↗

Genetic and Phenotypic Basis of Autosomal Dominant Parkinson's Disease in a Large Multi-Center CohortSemantic proximity Read ↗

Genetic risk factors in Finnish patients with Parkinson's disease.Semantic proximity Read ↗

Comprehensive genetic screening of the South African Parkinson’s disease study collection using the NeuroBooster arraySemantic proximity Read ↗

Comprehensive sequencing of the LRRK2 gene in patients with familial Parkinson's disease from North Africa.Semantic proximity Read ↗

Rare-Variant Burden Analysis of Dystonia Genes in Parkinson’s DiseaseSemantic proximity Read ↗

Pipeline to gene discovery - Analysing familial Parkinsonism in the Queensland Parkinson's Project.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.