Article
Gene Panel Sequencing Identifies Novel Pathogenic Mutations in Moroccan Patients with Familial Parkinson Disease.
Journal of molecular neuroscience : MN - 1 Jan 2021
Smaili Imane, Tesson Christelle, Regragui Wafa, Bertrand Hélène, Rahmani Mounia, Bouslam Naima, Benomar Ali, Brice Alexis, Lesage Suzanne, Bouhouche Ahmed
Abstract excerpt
In the past two decades, genetic studies of familial forms of Parkinson's disease (PD) have shown evidence that PD has a significant genetic component. Indeed, 12 genes are strongly involved in PD causality, three of them having dominant inheritance and 9 causing early-onset autosomal recessive forms, including 3 with a typical PD and 6 with an atypical parkinsonism. The aim of this study was to determine the...
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