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Article

The upper and lower respiratory tract microbiome in severe aspiration pneumonia

6 May 2023

Abstract excerpt

Uncertainty persists whether anaerobic bacteria represent important pathogens in aspiration pneumonia. In a nested case-control study of mechanically ventilated patients classified as macro-aspiration pneumonia (MAsP, n = 56), non-macro-aspiration pneumonia (NonMAsP, n = 91), and uninfected controls (n = 11), we profiled upper (URT) and lower respiratory tract (LRT) microbiota with bacterial 16S rRNA gene...

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PMID: 37250794
DOI: 10.1016/j.isci.2023.106832

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