Article
Respiratory Tract Dysbiosis Is Associated with Worse Outcomes in Mechanically Ventilated Patients.
American journal of respiratory and critical care medicine - 15 Dec 2020
Kitsios Georgios D, Yang Haopu, Yang Libing, Qin Shulin, Fitch Adam, Wang Xiao-Hong, Fair Katherine, Evankovich John, Bain William, Shah Faraaz, Li Kelvin, Methé Barbara, Benos Panayiotis V, Morris Alison, McVerry Bryan J
Abstract excerpt
Rationale: Host inflammatory responses have been strongly associated with adverse outcomes in critically ill patients, but the biologic underpinnings of such heterogeneous responses have not been defined.Objectives: We examined whether respiratory tract microbiome profiles are associated with host inflammation and clinical outcomes of acute respiratory failure.Methods: We collected oral swabs, endotracheal...
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