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CRISPR/Cas9 for hepatitis B virus infection treatment

1 May 2023

Abstract excerpt

Hepatitis B virus (HBV) infection remains a global health challenge. Despite the availability of effective preventive vaccines, millions of people are at risk of cirrhosis and hepatocellular carcinoma. Current drug therapies inhibit viral replication, slow the progression of liver fibrosis and reduce infectivity, but they rarely remove the covalently sealed circular DNA (cccDNA) of the virus that causes HBV...

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PMID: 37249290
DOI: 10.1002/iid3.866

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