Article
Serotonin and serotonin transporter gene variant in rotating shift workers.
Sleep - 1 Aug 2007
Sookoian Silvia, Gemma Carolina, Gianotti Tomas Fernández, Burgueño Adriana, Alvarez Azucena, González Claudio Daniel, Pirola Carlos Jose
Abstract excerpt
STUDY OBJECTIVES: Because serotonin (5-HT) is a neurotransmitter associated with circadian rhythm regulation, we explored a possible relation among 5-HT, serotonin metabolite, 5-hydroxyindolacetic acid (5HIAA), and the functional polymorphism of the serotonin transporter gene (SLC6A4) promoter with rotating shift work. DESIGN AND PARTICIPANTS: 683 men were included in this study: 437 day workers were compared...
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