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Article

HtrA4 may play a major role in inhibiting endothelial repair in pregnancy complication preeclampsia

25 Feb 2019

Abstract excerpt

Preeclampsia (PE) is a life-threatening complication of human pregnancy with no effective treatment other than premature delivery. It is hallmarked by systemic endothelial injury/dysfunction which is believed to be caused by abnormal levels/types of placenta-derived factors that are circulating in the maternal blood. Emerging evidence suggests that endothelial repair is also dysregulated in PE, as circulating...

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PMID: 30804477
DOI: 10.1038/s41598-019-39565-9

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