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Article

Potential Aromatase Inhibitors from Centella asiatica with Non-synonymous SNPS - A Computational Approach.

Current computer-aided drug design - 1 Jan 2024

Temkar Sheshadri S, Sridhara Amruta, Mallur Dhrithi Jayasimha, Shivaprakash Deepak Ishwara, Iyengar Divya, Das Nritam, C Benedict Paul

Abstract excerpt

BACKGROUND: Aromatase inhibitors are used in the treatment of breast cancer as they are effective in decreasing the concentration of estrogen. As SNPs impact the efficacy or toxicity of drugs, evaluating them with mutated conformations would help in identifying potential inhibitors. In recent years, phytocompounds have been under scrutiny for their activity as potential inhibitors. OBJECTIVE: In this study, we...

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PMID: 37231718
DOI: 10.2174/1573409919666230525151933

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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