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Article

Dynamins in human diseases: differential requirement of dynamin activity in distinct tissues.

Current opinion in cell biology - 1 Apr 2023

Laiman Jessica, Lin Shan-Shan, Liu Ya-Wen

Abstract excerpt

Dynamin, a 100-kDa GTPase, is one of the most-characterized membrane fission machineries catalyzing vesicle release from plasma membrane during endocytosis. The human genome encodes three dynamins: DNM1, DNM2 and DNM3, with high amino acid similarity but distinct expression patterns. Ever since the discoveries of dynamin mutations associated with human diseases in 2005, dynamin has become a paradigm for studying...

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Identifiers

PMID: 37230036
DOI: 10.1016/j.ceb.2023.102174

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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