Article
Dynamin-2 in nervous system disorders.
Journal of neurochemistry - 1 Jan 2014
González-Jamett Arlek M, Haro-Acuña Valentina, Momboisse Fanny, Caviedes Pablo, Bevilacqua Jorge A, Cárdenas Ana M
Abstract excerpt
Dynamin-2 is a pleiotropic GTPase whose best-known function is related to membrane scission during vesicle budding from the plasma or Golgi membranes. In the nervous system, dynamin-2 participates in synaptic vesicle recycling, post-synaptic receptor internalization, neurosecretion, and neuronal process extension. Some of these functions are shared with the other two dynamin isoforms. However, the involvement of...
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