Article
Effect of melatonin on ATG2B-mediated autophagy regulation in sheep granulosa cells with different FecB genotypes.
Journal of pineal research - 1 Aug 2023
Liu Yu-Fang, Liu Zi-Yi, Li Wen-Tao, Wang Peng, Wang Xiang-Yu, Di Ran, He Xiao-Yun, Chu Ming-Xing
Abstract excerpt
Melatonin (MLT) protects cells by reducing reactive oxygen species (ROS) levels, which are key for inducing cellular autophagy. The aim of this study was to investigate the molecular mechanisms underlying MLT regulation of autophagy in granulosa cells (GCs) with BMPR-1B homozygous (FecB BB) and wild type (FecB ++) mutations. GCs collected from small-tailed Han sheep with different FecB genotypes were typed using...
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