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Nucleocapsid-specific T cell responses associate with control of SARS-CoV-2 in the upper airways before seroconversion

24 May 2023

Abstract excerpt

Abstract Despite intensive research since the emergence of SARS-CoV-2, it has remained unclear precisely which components of the early immune response protect against the development of severe COVID-19. Here, we perform a comprehensive immunogenetic and virologic analysis of nasopharyngeal and peripheral blood samples obtained during the acute phase of infection with SARS-CoV-2. We find that soluble and...

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PMID: 37225706
DOI: 10.1038/s41467-023-38020-8

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