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Article

APOBEC3F Is a Mutational Driver of the Human Monkeypox Virus Identified in the 2022 Outbreak.

The Journal of infectious diseases - 11 Nov 2023

Suspène Rodolphe, Raymond Kyle A, Boutin Laetitia, Guillier Sophie, Lemoine Frédéric, Ferraris Olivier, Tournier Jean-Nicolas, Iseni Frédéric, Simon-Lorière Etienne, Vartanian Jean-Pierre

Abstract excerpt

BACKGROUND: On May 6, 2022, a powerful outbreak of monkeypox virus (MPXV) had been reported outside of Africa, with many continuing new cases being reported around the world. Analysis of mutations among the 2 different lineages present in the 2021 and 2022 outbreaks revealed the presence of G->A mutations occurring in the 5'GpA context, indicative of APOBEC3 cytidine deaminase activity. METHODS: By using a...

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Identifiers

PMID: 37224627
DOI: 10.1093/infdis/jiad165
PMCID: PMC11009509

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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