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Article

The frequency of rs2231142 in ABCG2 among Asian subgroups: implications for personalized rosuvastatin dosing.

Pharmacogenomics - 1 Jan 2023

Alrajeh Khalifa, Roman Youssef M

Abstract excerpt

Statins are widely used medications for the primary and secondary prevention of cardiovascular diseases. Statin-induced musculoskeletal symptoms are the primary adverse drug events contributing to poor adherence to lipid-lowering therapy. Rosuvastatin is characterized by interindividual differences in systemic exposure among different patient population subgroups. The missense variant Q141K within ABCG2, highly...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36651271
DOI: 10.2217/pgs-2022-0155
PMCID: PMC9979151

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