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Article

Integrative analysis of mutated genes and mutational processes reveals novel mutational biomarkers in colorectal cancer.

BMC bioinformatics - 19 Apr 2022

Dashti Hamed, Dehzangi Iman, Bayati Masroor, Breen James, Beheshti Amin, Lovell Nigel, Rabiee Hamid R, Alinejad-Rokny Hamid

Abstract excerpt

BACKGROUND: Colorectal cancer (CRC) is one of the leading causes of cancer-related deaths worldwide. Recent studies have observed causative mutations in susceptible genes related to colorectal cancer in 10 to 15% of the patients. This highlights the importance of identifying mutations for early detection of this cancer for more effective treatments among high risk individuals. Mutation is considered as the key...

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Identifiers

PMID: 35439935
DOI: 10.1186/s12859-022-04652-8
PMCID: PMC9017053

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