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Article

Aspirin loaded extracellular vesicles inhibit inflammation of macrophages via switching metabolic phenotype in periodontitis.

Biochemical and biophysical research communications - 30 Jul 2023

Shi Yuanyuan, Zhang Ruijie, Da Ningning, Wang Yiming, Yang Jianhua, Li Bei, He Xiaoning

Abstract excerpt

OBJECTIVES: Changes of macrophage in the local immune microenvironment of periodontitis cause alveolar bone resorption. This study aims to investigate the effect of a new drug delivery method of aspirin on the immune microenvironment of periodontitis to promote alveolar bone repair, and to explore mechanism of aspirin's effect on macrophage. METHODS: We isolated extracellular vesicles (EVs) from periodontal stem...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 37207561
DOI: 10.1016/j.bbrc.2023.05.024

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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