Article

Paracrine Signals from HIV-1 Infected Immune Cells Reprogram Cervical Cancer Pathways

2025-06-07

Abstract excerpt

Persistent infection with human papillomavirus (HPV) is the primary cause of cervical cancer worldwide. Notably, women co-infected with HPV and human immunodeficiency virus type 1 (HIV-1) have a six-fold higher lifetime risk of developing cervical cancer compared to those without HIV, even when adhering to antiretroviral therapy (ART) and achieving T-cell reconstitution. While chronic HIV-1 infection is known to c...

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Literature Corpus work: 6907117b-4d1d-5190-b733-fce25e964bec
DOI: 10.1101/2025.06.06.658239

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