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Article

Pathological characteristics and immune microenvironment of SMARCA4-deficient undifferentiated uterine sarcoma.

Diagnostic pathology - 16 May 2023

Gao Jie, Fan Ruirui, Chen Dahong, Hou Jinlin, Chen Hanlin, Lu Mingzhi

Abstract excerpt

SMARCA4-deficient undifferentiated uterine sarcoma (SDUS) is a highly invasive single-gene malignant tumor caused by mutations in the SMARCA4 gene. SDUS has a poor prognosis, with no established treatment strategy at present. Further, there is a lack of relevant research on the role of the immune microenvironment in SDUS worldwide. Here, we report a case of SDUS that was diagnosed and analysed using...

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Identifiers

PMID: 37194064
DOI: 10.1186/s13000-023-01347-3
PMCID: PMC10186742

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