Article
Secretor and Salivary ABO Blood Group Antigen Status Predict Rotavirus Vaccine Take in Infants.
The Journal of infectious diseases - 1 Mar 2017
Kazi Abdul Momin, Cortese Margaret M, Yu Ying, Lopman Benjamin, Morrow Ardythe L, Fleming Jessica A, McNeal Monica M, Steele A Duncan, Parashar Umesh D, Zaidi Anita K M, Ali Asad
Abstract excerpt
Histo-blood group antigens (HBGAs) expressed on enterocytes are proposed receptors for rotaviruses and can be measured in saliva. Among 181 Pakistani infants in a G1P[8] rotavirus vaccine trial who were seronegative at baseline, anti-rotavirus immunoglobulin A seroconversion rates after 3 vaccine doses differed significantly by salivary HBGA phenotype, with the lowest rate (19%) among infants who were...
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