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Article

Ferroptosis vulnerability in FLT3-mutant leukemia.

Trends in cancer - 1 Jul 2023

Lee Hyemin, Zhuang Li, Gan Boyi

Abstract excerpt

Resistance to FLT3 inhibition is a prevalent challenge in managing FLT3-mutant acute myeloid leukemia (AML). A recent study by Sabatier et al. discovered ferroptosis vulnerability in FLT3-mutant AML and they propose a promising therapeutic approach of combining FLT3 inhibitors with ferroptosis inducers for treating this type of cancer.

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Identifiers

PMID: 37173186
DOI: 10.1016/j.trecan.2023.04.011

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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