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Susceptibility of acute myeloid leukemia cells to ferroptosis and evasion strategies

25 Sept 2023

Abstract excerpt

Acute myeloid leukemia (AML) is a highly aggressive hematologic malignancy with a 5-year survival rate of less than 30%. Continuous updating of diagnostic and therapeutic strategies has not been effective in improving the clinical benefit of AML. AML cells are prone to iron metabolism imbalance due to their unique pathological characteristics, and ferroptosis is a novel cell death mode that is dominated by three...

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PMID: 37818101
DOI: 10.3389/fmolb.2023.1275774

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