Article
Mutation detection of urinary cell-free DNA via catch-and-release isolation on nanowires for liquid biopsy.
Biosensors & bioelectronics - 15 Aug 2023
Takahashi Hiromi, Yasui Takao, Hirano Masaki, Shinjo Keiko, Miyazaki Yusuke, Shinoda Wataru, Hasegawa Takeshi, Natsume Atsushi, Kitano Yotaro, Ida Mikiko, Zhang Min, Shimada Taisuke, Paisrisarn Piyawan, Zhu Zetao, Ohka Fumiharu, Aoki Kosuke, Rahong Sakon, Nagashima Kazuki, Yanagida Takeshi, Baba Yoshinobu
Abstract excerpt
Cell-free DNA (cfDNA) and extracellular vesicles (EVs) are molecular biomarkers in liquid biopsies that can be applied for cancer detection, which are known to carry information on the necessary conditions for oncogenesis and cancer cell-specific activities after oncogenesis, respectively. Analyses for both cfDNA and EVs from the same body fluid can provide insights into screening and identifying the molecular...
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