Article
Adsorption of SARS-CoV-2 Spike (N501Y) RBD to Human Angiotensin-Converting Enzyme 2 at a Lipid/Water Interface.
The journal of physical chemistry. B - 25 May 2023
Rozak Harison, Nihonyanagi Satoshi, Myalitsin Anton, Roy Subhadip, Ahmed Mohammed, Tahara Tahei, Rzeznicka Izabela I
Abstract excerpt
The receptor binding domain (RBD) of spike proteins plays a crucial role in the process of severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) attachment to the human angiotensin-converting enzyme 2 (ACE2). The N501Y mutation and later mutations introduced extra positive charges on the spike RBD and resulted in higher transmissibility, likely due to stronger binding with the highly negatively charged...
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