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Giant Cell Tumors With HMGA2::NCOR2 Fusion

12 May 2023

Abstract excerpt

Giant cell tumors (GCTs) with high mobility group AT-Hook 2 ( HMGA2 )::nuclear receptor corepressor 2 ( NCOR2 ) fusion are rare mesenchymal tumors of controversial nosology, which have been anecdotally reported to respond to CSFR1 inhibitors. Here, we performed a comprehensive study of 6 GCTs with HMGA2::NCOR2 fusion and explored their relationship with other giant cell-rich neoplasms. Tumors occurred in 4...

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PMID: 37170907
DOI: 10.1097/pas.0000000000002051

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