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Article

RUNX2 mutation inhibits the cellular senescence of dental follicle cells via ERK signalling pathway.

Oral diseases - 1 Apr 2024

Ji LingLi, Li Jie, Liu Dandan, Qiao Yanchun, Zhao Weiwei, Liu Yang, Zheng Shuguo

Abstract excerpt

OBJECTIVE: The aim of this study was to explore the regulatory effect of RUNX2 mutation on dental follicle cells (DFCs) senescence and clarify the underlying mechanism. This study aimed to explore the basis for a novel mechanism of delayed permanent tooth eruption in cleidocranial dysplasia (CCD) patients. MATERIALS AND METHODS: Dental follicles were collected from a CCD patient and healthy controls....

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Identifiers

PMID: 37154397
DOI: 10.1111/odi.14607

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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