Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Short telomeres correlate with a strong induction of cellular senescence in human dental follicle cells

3 Apr 2019

Abstract excerpt

BACKGROUND: Dental follicle cells (DFCs) are dental stem cells and interesting options for regenerative therapies in dentistry. However, DFCs acquire replicative senescence in long-term cultures, but little is known about molecular processes. In previous studies, we observed that DFC cell lines become senescent at different rates. We hypothesized that short telomere length and increased DNA damage with genomic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hair Growth and Disorders
Share to Mesenchymal stem cell research
Share to Telomeres, Telomerase, and Senescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31041893
DOI: 10.1186/s12860-019-0185-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Short telomeres correlate with a strong induction of cellular senescence in human dental follicle cellsPMID 31041893Read ↗

Drug-induced premature senescence model in human dental follicle stem cells.Semantic proximity Read ↗

A transcriptomic analysis of dental pulp stem cell senescence in vitroSemantic proximity Read ↗

RUNX2 mutation inhibits the cellular senescence of dental follicle cells via ERK signalling pathway.Semantic proximity Read ↗

Variation in human dental pulp stem cell ageing profiles reflect contrasting proliferative and regenerative capabilitiesSemantic proximity Read ↗

Analysis of Senescence-Related Differentiation Potentials and Gene Expression Profiles in Human Dental Pulp Stem CellsSemantic proximity Read ↗

Attenuated regenerative properties in human periodontal ligament–derived stem cells of older donor ages with shorter telomere length and lower SSEA4 expressionSemantic proximity Read ↗

Comparative characterization of SHED and DPSCs during extended cultivation inï¿½vitroSemantic proximity Read ↗

Telomere Attrition Occurs during Ex Vivo Expansion of Human Dental Pulp Stem CellsSemantic proximity Read ↗

Aging and Senescence of Dental Pulp and Hard Tissues of the ToothSemantic proximity Read ↗

Alu methylation level, morphological, and senescence changes during in vitro aging of human dental pulp stem cellsSemantic proximity Read ↗

Senescence-associated genes in normal human oral keratinocytesSemantic proximity Read ↗

Cellular senescence contributes to radiation-induced hyposalivation by affecting the stem/progenitor cell nicheSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.