Article
[Association of leptin level and leptin receptor gene polymorphisms with susceptibility to severe pre-eclampsia].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Oct 2011
Guan Li-xue, Gao Li, Gao Ying, Li Hai-bo, Yu Feng-fei, Du Xin-ying, Jiang Hong
Abstract excerpt
OBJECTIVE: To evaluate the association of serum leptin concentrations and polymorphisms of G1019A and A223G of leptin receptor gene (LEPR) with severe pre-eclampsia. MEHTODS: A case-control study was carried out in 207 patients with severe pre-eclampsia (SPE group) and 252 healthy pregnant women (control group) during the third trimester of pregnancy. The serum leptin was determined by enzyme-linked immunosorbent...
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