Article
Telomere length assessment and molecular characterization of TERT gene promoter in periampullary carcinomas.
Gene - 15 Jul 2023
Gregório Cleandra, Thakur Shefali, Camara Rivero Raquel, Márcia Dos Santos Machado Simone, Cuenin Cyrille, Carreira Christine, White Valerie, Cree Ian A, Vukojevic Katarina, Glavina Durdov Merica, Bersch Osvaldt Alessandro, Ashton-Prolla Patricia, Herceg Zdenko, Talukdar Fazlur Rahman
Abstract excerpt
Genetic and epigenetic alterations of the telomere maintenance machinery like telomere length and telomerase reverse transcriptase (encoded by TERT gene) are reported in several human malignancies. However, there is limited knowledge on the status of the telomere machinery in periampullary carcinomas (PAC) which are rare and heterogeneous groups of cancers arising from different anatomic sites around the ampulla...
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